Pregnane X Receptor Activator Rifampin Increases Blood Pressure and Stimulates Plasma Renin Activity
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چکیده
منابع مشابه
Rifaximin is a gut-specific human pregnane X receptor activator.
Rifaximin, a rifamycin analog approved for the treatment of travelers' diarrhea, is also beneficial in the treatment of multiple chronic gastrointestinal disorders. However, the mechanisms contributing to the effects of rifaximin on chronic gastrointestinal disorders are not fully understood. In the current study, rifaximin was investigated for its role in activation of the pregnane X receptor ...
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Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension. For the total hour; arterial A II was 5.2 ± 1.0 pg/ml; venous A II was 4.2 ± 0.6 pg/ml; and plasma aldosterone was 5.0 ± 0.45 ng/100 ml. All values were lower than corresponding values for normal subjects on a high ...
متن کاملRelation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension.
Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension. For the total hour; arterial A II was 5.2 +/- 1.0 pg/ml; venous A II was 4.2 +/- 0.6 pg/ml; and plasma aldosterone was 5.0 +/- 0.45 ng/100 ml. All values were lower corresponding values for normal subjects on a high...
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ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2020
ISSN: 0009-9236,1532-6535
DOI: 10.1002/cpt.1871